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In this article, we will delve into the key concepts surrounding the molecular basis of inheritance as outlined in NCERT biology textbooks. The concept of the molecular basis of inheritance is a fundamental pillar of biology, providing insights into the mechanisms that govern the transmission of genetic information from one generation to the next. This crucial topic plays a central role in our understanding of genetics and the way traits are inherited. molecular basis of inheritance ncert solutions. Molecular basis of inheritance ncert notes pdf.
At the heart of understanding the molecular basis of inheritance is the molecule known as deoxyribonucleic acid, or DNA. DNA is often described as the “blueprint of life” because it carries all the genetic information necessary for the development, functioning, and reproduction of living organisms.
The structure of DNA, first elucidated by James Watson and Francis Crick in 1953, is a double helix composed of nucleotide units. Each nucleotide consists of a sugar (deoxyribose), a phosphate group, and one of four nitrogenous bases: adenine (A), thymine (T), guanine (G), or cytosine (C). It is the sequence of these bases along the DNA molecule that encodes genetic information.
DNA replication is a critical process in the molecular basis of inheritance. Before a cell can divide, it must make an exact copy of its DNA to pass on to the daughter cells. This process ensures that each new cell receives an identical set of genetic information. DNA replication involves the separation of the DNA strands and the synthesis of two new complementary strands by matching base pairs. This process is highly accurate, with built-in proofreading mechanisms to minimize errors.
The genetic information stored in DNA is not directly used to build the molecules that perform the work in cells. Instead, an intermediate molecule called ribonucleic acid (RNA) is employed. RNA, a single-stranded molecule, is synthesized based on the DNA template through a process known as transcription.
One crucial type of RNA, called messenger RNA (mRNA), carries the genetic information from the DNA in the cell’s nucleus to the ribosomes, where protein synthesis occurs. This transfer of information is essential for the production of proteins, the workhorses of the cell.
Proteins are synthesized in a process known as translation. Transfer RNA (tRNA) molecules bring specific amino acids to the ribosome, where they are assembled into a protein based on the instructions encoded in the mRNA. The sequence of codons (groups of three nucleotides) in the mRNA dictates the order of amino acids, ultimately determining the structure and function of the protein.
The genetic code is a universal code that translates the information in DNA into the language of proteins. It is a triplet code, meaning that each combination of three nucleotides (a codon) corresponds to a specific amino acid or a “stop” signal that ends protein synthesis.
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The genetic code is highly redundant, meaning that multiple codons can code for the same amino acid. This redundancy provides a degree of error tolerance in protein synthesis and is a testament to the robustness of the genetic code.
Mutations are changes in the DNA sequence, and they are a natural part of genetic variation. Mutations can occur for various reasons, such as exposure to radiation, chemicals, or errors during DNA replication. Some mutations can be harmful and lead to diseases, while others can be neutral or even beneficial, contributing to the diversity of life.
Understanding mutations is essential in the context of the molecular basis of inheritance because they are the raw material for evolution. Over long periods of time, beneficial mutations can accumulate, leading to the development of new traits and species.
The study of the molecular basis of inheritance also provides insights into how traits are inherited from one generation to the next. Inheritance patterns can be broadly categorized into two main types: Mendelian and non-Mendelian.
Mendelian inheritance, based on the work of Gregor Mendel, follows the principles of dominance, segregation, and independent assortment. In Mendelian inheritance, traits are determined by single genes, and the inheritance of one trait does not influence the inheritance of another trait.
Mendel’s experiments with pea plants revealed the concept of dominant and recessive alleles. Dominant alleles are expressed when present, whereas recessive alleles are only expressed when both alleles are recessive.
Non-Mendelian inheritance patterns involve more complex genetic interactions. Examples include incomplete dominance, codominance, and polygenic inheritance. Incomplete dominance occurs when a heterozygote (individual with two different alleles) displays an intermediate phenotype. Codominance involves the simultaneous expression of both alleles in a heterozygote.
Polygenic inheritance occurs when multiple genes contribute to a single trait, leading to a wide range of possible phenotypes. Human traits like height, skin color, and eye color are influenced by polygenic inheritance.
The molecular basis of inheritance is a fascinating and complex field of study that underpins our understanding of genetics and heredity. DNA, replication, transcription, translation, and the genetic code are the cornerstones of this field, enabling us to unravel the mysteries of how genetic information is passed from one generation to the next.
While this article provides an overview of the topic as of my last knowledge update in September 2021, it’s important to note that scientific research in this field continues to evolve. For the most up-to-date information and a more detailed understanding, it is advisable to refer to the latest NCERT biology textbooks and scientific literature.
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